Sixty-nine patients were included in our study: 17 from healthy volunteers (11 male and 6 female) and 52 from diabetic patients (30 male and 22 female), including 12 patients with type I diabetes mellitus and 40 with type II diabetes mellitus, of whom 26 were insulin-dependent at the time of inclusion (Table 1). This evidence concerns the gene INS and type 1 diabetes mellitus.