CD86 and acute lymphoblastic leukemia: Remarkably, previously reported HDAC7 targets such as MMP9 and CD86 were robustly upregulated, similar to the effect of forced HDAC7 expression [26] (Supplementary Fig. S6C), reinforcing the idea that HDAC7 induction is associated with changes in overall t(4;11) pro-B-ALL cells transcriptome.