Tumor-associated neutrophils (TANs) display elevated PANoptosis gene expression and play pro-tumor activity with DCs via GATA-binding protein 2 (GATA2)-HMGB1-TIM-3 pathway, thereby hindering anti-tumor immunity and facilitating immune evasion of non-small cell lung cancer cells [96]. The gene discussed is GATA2; the disease is non-small cell lung carcinoma.