Prototypic group 3 MBs are predominantly comprised of undifferentiated progenitor-like cells with high MYC activity [21], suggesting that the undifferentiated transcriptional program of these cells may be connected to their aberrant expression of multiple MAGEs. However, the expression patterns of MYC and MAGEs (Figs. 1C, 1D, 2C, and 3A), along with the viability data from the D341 MYC-amplified medulloblastoma cell line (Figs. 4D, 4E, and S5B–D), suggest that MAGE expression may be independent of MYC expression. The gene discussed is MYC; the disease is medulloblastoma.