Increased age and BMI, mandibular infections, infections post-extraction or post-augmentation, clinical symptoms at admission (restricted mouth opening, dysphagia, non-palpable mandibular margin), elevated inflammatory markers (CRP, leukocytes, neutrophils, procalcitonin), and cervical drainage were significantly associated with higher recurrence risk and increased LOS (p < 0.05). The gene discussed is CRP; the disease is infection.