CD8A and T-cell large granular lymphocyte leukemia: The CD8 + STAT3 T-LGLL group, characterized by a more symptomatic disease, was distinguished from the other three subtypes (from now on considered as a single group, named “others”, OTH) and from CTR, confirming a peculiar profile of STAT3-mutated cases, in line with the results reported in Fig. 1B–D.