SP2 and neoplasm: We mapped binding and quantified increased and decreased occupancies of 11 TFs (ASCL1, FOXA1, MYC, NEUROD1, NFIB, NRF1, POU2F3, p53, P73, SP2, and YAP1) in chemotherapy-treated relative to control tumours, for which transcripts were detectable (Fig. 4B and Supplementary Fig. 5A).