Effects of this type might be relevant to the heart because of PIEZO1’s role in pericardial effusion (Ranade et al. 2014a; Ludlow et al. 2023), and the suggestion that lymphatic stimulators may accelerate the clearance of damage products and unwanted inflammatory mediators after cardiac ischemia (Cooper et al. 2024). This evidence concerns the gene PIEZO1 and myocardial ischemia.