MAPT and Alzheimer disease: The role of EVs in Alzheimer's disease has received considerableattention, with research indicating that EVs contain several proteinsthat are relevant for the disease and may make valuable biomarkers.EVs derived from neurons and glial cells can carry pathological formsof tau protein, which aggregates in Alzheimer's disease as wellasin other tauopathies, and elevated levels of tau-containing EVs incerebrospinal fluid and blood are associated with disease severityand progression.