Another innovative techniqueincorporates a novel nanoprobe basedon dissociation-enhanced luminescence technology, enabling the analysisof multiple surface proteins on small EVs and facilitating the accuratediagnosis of diseases like breast cancer. In this technique, small EVs are captured on a solid surface (likea microplate) via antibodies that specifically target CD63, a transmembraneprotein commonly found on the surface of small EVs. This evidence concerns the gene CD63 and breast cancer.