However, research specificallyfocused on EVs carrying CD71 remains limited. CD71 is predominantly expressed on erythroid cells, whereit plays a key role in iron uptake, making it a potential biomarkerfor assessing iron status., EVs that express CD71could also suggest elevated cellular growth, which is often seen incancers of the small bowel mucosa and in leukemia and lymphoma. This evidence concerns the gene TFRC and leukemia.