CFL1 and cancer: Actin dynamics influence the formation and releaseof EVs from the parent cell, the sorting and packaging of cargo intoEVs, and the subsequent binding and uptake of EVs by target cells. Actin levels in EVs can mirror processes relatedto cellular migration, cancer invasion, wound healing, or inflammatoryresponses. Cofilin, which regulatesactin dynamics, can signal cellular stress or injury when detectedin EVs.