Dominant variants in COL8A2 (MIM *120252, #136800), ZEB1 (MIM *189909, #613270), SLC4A11 (MIM *610206, #613268), AGBL1 (MIM *615496, #615523) and LOXHD1 (MIM *613072) have been reported to cause FECD but are much less common than the CTG18.1 trinucleotide repeat expansion in intron 2 of TCF4. The gene discussed is TCF4; the disease is Fuchs endothelial corneal dystrophy.