In multivariable analysis after adjusting for age, BMI, ECOG performance status, treatment, PD‐L1 status, and development of AKI remained a statistically significant predictor of reduced12‐month OS (HR: 1.752, 95% CI: 1.066–2.880, p = 0.027) (Figure 3). This evidence concerns the gene CD274 and acute kidney injury.