Consistent with the diagnosis of advanced fibrosis/liver cirrhosis were the alterations in biochemical profile (plasma albumin, liver enzymes, total and LDL cholesterol) and the results of haemochromocytometric analysis, showing a trilinear cytopenia, with mean platelet count in the range of moderate thrombocytopenia (median difference between healthy subjects and cirrhotic patients: −162.5 × 103/μL, 95% CI −173.0 to −136.0; between ≤ F2 and F3–F4 patients: −156.0 × 103/μL, 95% CI −174.0 to −138.0) (see Figure S1, Panel A). This evidence concerns the gene ALB and cirrhosis of liver.