Figure 1 presents an oncoplot of somatic mutations detected in astrocytoma patients, grouped by clinical seizure presentation. Samples with seizures (red) and without seizures (gray) are visually separated by a dashed vertical line. Mutation types are color-coded, and bar plots indicate mutation burden per sample (top) and mutation frequency per gene (right). Distinct mutational profiles were observed between the groups, with higher frequencies of IDH1, GRIN2B, and BRAF mutations in patients with seizures. The gene discussed is BRAF; the disease is astrocytoma (excluding glioblastoma).