CDKN2A and meningioma: IOMM-Lee has been widely used in meningioma research and is known to harbor pTERT hotspot mutation (c.-124C>T) and a 3.6-kb deletion affecting the CDKN2A gene (Chr9:21971209–21974828).20 We performed a complex analysis of the effects of EPZ-6438 on this cell line both in vitro and in vivo, using a heterotopic mouse xenograft model.