Concerning the genetic signatures using cox1 and ITS-2/18S markers together, in the 642 eggs from patients with urinary schistosomiasis, we describe a total of six mito-nuclear signatures, among which only one corresponds to pure S. haematobium (83.30%) and five (16.67%) to S. haematobium × S. Here, MT-CO1 is linked to urinary schistosomiasis.