IL22 and psoriasis: In psoriasis, curcumin exhibits its anti-inflammatory effects by reducing the expression of cytokines such as interleukin-17A (IL-17A), interleukin-17F (IL-17F), interleukin-22 (IL-22), IL-6, IL-1β, and TNF-α, and by inhibiting NF-κB activation (163).