At the national level, both the United States and China have made significant contributions to all of these key themes, particularly in the areas of the keywords: “tumor microenvironment,” “Epithelial ovarian cancer,” “PD - L1,” or “PD – 1,” “Chemotherapy,” “Targeted therapy,” “Biomarker,” “Immune checkpoint inhibitor,” and “Immune microenvironment.” “Immune checkpoint, “Italy shows less interest in themes related to “prognosis,” while Australia and Japan have lower levels of focus on “tumor microenvironment” related themes. The gene discussed is RPL17; the disease is ovarian carcinoma.