PRL and neoplasm: PitNETs are the most common tumor; while they occur in up to 20% of the population, they are often not detected clinically and may be found as incidental lesions on imaging or at autopsy.1 They have a prevalence of 78–116 cases per 100 000 people and an estimated incidence of 4.12/100 000 population per year.1 Prolactin-producing tumors are the most common functioning tumors and most are treated medically; their true incidence is not captured in cancer statistics.