COL4A3 and diabetic kidney disease: Although previously reported variants were not commonly detected in our patients, particularly the SNPs rs1516446, rs536174, rs598819, rs2881142, rs4623610, and rs1266736 in the collagen-coding genes could be regarded in further investigations. Importantly, in a genome-wide association study conducted in a European cohort, a SNP (rs55703767) in the COL4A3 gene was linked to diabetic kidney disease [52], underlying the value of SNPs in the collagen-coding genes as a risk factor in renal diseases.