None of the CF causing variants were detected; however, genotype analysis revealed both alleles carried 12 dinucleotide thymidine guanine repeats (TG) 12/12 at the junction of exon 8 and exon 9, combined with methionine (M) at position 470, which is known to reduce the amount of intact CFTR proteins due to affecting the efficiency of exon 9 splicing (Table 1). This evidence concerns the gene CFTR and cystic fibrosis.