(16) also discovered the core genes related to Alzheimer’s disease (AD) and sleep disorders via gene module analysis, including ATP5A1, UQCRC2, ATP5B, UQCRC1, COX5A, SOD1, GAPDH, NDUFV2, NDUFA9, and NDUFS3 genes. Here, GAPDH is linked to early-onset autosomal dominant Alzheimer disease.