NR3C1 and major depressive disorder: In the nAcc region, dopamine metabolic process, MHC class II protein complex, and MHC class II receptor activity were the top enriched pathways in SZ patients (Figure 2D), regulation of type B pancreatic cell proliferation, filopodium, and glucocorticoid receptor binding were the top enriched pathways in BD patients (Figure 2E), and response to peptide hormone, phosphatidylinositol 3-kinase complex, and 1-phosphatidylinositol-3-kinase regulator activity were the top enriched pathways in MDD patients (Figure 2F).