FABP4 and hepatocellular carcinoma: For instance, studies have shown that high expression of FABP1 in hepatocellular carcinoma is associated with increased tumor aggressiveness[192], and elevated gene expression of FABP4 in normal tissue were associated with worse overall survival of patients with ER-positive breast cancer (P-value = 0.0089)[193], highlighting their potential as molecular predictors of recurrence and long-term prognosis.