Cancerous tissues and corresponding paracancerous tissues of 30 HCC patients were prepared into tissue chips, and it was found that the expressions of PKM2, LDHA, c‐MYC, SOX2, CD44 and CD133 in cancerous tissues were significantly higher than those in corresponding paracancerous tissues (p < 0.05), with statistical significance (Figure 1E). Here, PKM is linked to hepatocellular carcinoma.