MAOB and post-traumatic stress disorder: Although MAOB has been described as a dopamine-degradation enzymes,47 we have recently shown that MAOA primarily degrades dopamine, whereas MAOB selectively regulates tonic GABA inhibition in the striatal neurons.48 Similar to the previous findings, our dopamine imaging results revealed that PTSD-like mice exhibited reduced striatal dopamine release, which was restored to control levels following KDS2010 treatment.