MAOB and post-traumatic stress disorder: Previous studies have shown that enhancing GABAergic neurotransmission reduced conditioned freezing in female PTSD-like mice.51,52 Although our preclinical studies mostly employed male mice, this choice was made to minimize variability, particularly because MAOB is located on the X chromosome, making males a more straightforward model for assessing MAOB effects without the potential confound of X-inactivation.