SLC1A5 and central nervous system cancer: For instance, in U87-MG glioma and A549 cells, alanine uptake is facilitated by SNAT1, SNAT2, SNAT5, SLC6A15 (B0AT2), SLC7A6 (y+LAT2), SLC1A4 (ASCT1), and SLC1A5 (ASCT2), and many of these transporters are also involved in glutamine transport (22).