Studies suggest a potential link between periodontal disease and hypertension,15,16,17 which may be partly due to elevated levels of inflammatory markers, such as C-reactive protein (CRP), fibrinogen and white blood cells associated with periodontal conditions.18,19 These inflammatory markers are known contributors to hypertension and coronary heart disease.20,21,22,23,24 Furthermore, it has been demonstrated that CRP can predict hypertension independently of baseline blood pressure and other traditional risk factors.24 This evidence concerns the gene CRP and hypertensive disorder.