In the cardiovascular space, Chan and colleagues recently mapped a circulating proteome of post-myocardial infarction clinical events to differentially expressed genes from single-cell/single-nuclear RNA-seq from mice and humans with HF79, following a similar workflow and identifying several key canonical markers consistent with our study (e.g., THBS2, FSTL3). Here, FSTL3 is linked to myocardial infarction.