High CAV1 levels were independently associated with poor overall survival (hazard ratio = 1.744, p = 0.044), with the worst prognosis observed patients with viral hepatitis HCC (HBV: hazard ratio = 2.039, p = 0.025, HCV: hazard ratio = 1.768, p = 0.039) (Fig. 7F). This evidence concerns the gene CAV1 and animal viral hepatitis.