Multivariable binary logistic regression analysis revealed that RASP (OR = 2.968, 95% CI 1.279–6.890, P = 0.011), transapical TAVR approach (OR = 5.283, 95% CI 2.194–12.724, P < 0.001) and higher septal E/E′ (>27, OR = 2.599, 95% CI 1.152–5.863, P = 0.021) were independently associated with AKI post‐TAVR (Table 4). The gene discussed is HHAT; the disease is acute kidney injury.