According to the annotation of PD‐L1 expression and PD1 checkpoint pathway in cancer in the KEGG database (Figure S11, Supporting Information), the nuclear factor of activated T‐cells (NFAT) transcription factor family (NFATC1, NFATC2, and NFATC3) could mediate the transcriptional activation of PDL1 in the tumor cells, which was activated by ERK pathway. This evidence concerns the gene NFATC1 and cancer.