FLG and central nervous system cancer: The horizontal histogram showed the top 10 mutated genes in gliomas, including TP53, IDH1, ATRX, TTN, PTEN, EGFR, MUC16, NF1, RYR2, PIK3CA, LRP2, FLG, PKHD1, PCLO, and OBSCN, in the high‐IGLoS group (Figure S4A, Supporting Information), while IDH1, TP53, ATRX, CIC, TTN, FUBP1, PIK3CA, MUC16, NOTCH1, IDH2, SMARCA4, and PIK3R1 in the low‐IGLoS group (Figure S4C, Supporting Information).