On group level, the patients that classified as ALT/TERT TMM positive were older than those that classified as TMM negative or TMM positive (P value < 0.001 for both comparisons, Supplemental Fig. 2A), as expected as 11q-deleted neuroblastoma patients, which are enriched in the TMM positive class, are older at time of diagnosis than other genomic subgroups [3]. This evidence concerns the gene TERT and neuroblastoma.