Genetic analysis used a targeted dementia/FTD-ALS gene panel (APOE, APP, CHMP2B, CSF1R, DNAJC5, DNMT1, EPM2A, GRN, ITM2B, MAPT, NHLRC1, NOTCH3, OPTN, PRNP, PSEN1, PSEN2, SQSTM1, TARDBP, TBK1, TREM2, TUBA4A, TYROBP, UBQLN2, VCP), plus C9orf72 repeat expansion and APOE4 genotyping. Here, APOE is linked to frontotemporal dementia.