Genetic analysis used a targeted dementia/FTD-ALS gene panel (APOE, APP, CHMP2B, CSF1R, DNAJC5, DNMT1, EPM2A, GRN, ITM2B, MAPT, NHLRC1, NOTCH3, OPTN, PRNP, PSEN1, PSEN2, SQSTM1, TARDBP, TBK1, TREM2, TUBA4A, TYROBP, UBQLN2, VCP), plus C9orf72 repeat expansion and APOE4 genotyping. The gene discussed is TBK1; the disease is frontotemporal dementia.