CRP and metabolic syndrome: For the Framingham Risk Score, baseline inflammation levels and metabolic syndrome were not significantly associated with the score (difference in score per each SD increase in IL-6: -0.015, 95% CI: -0.499 to 0.488; TNF-alpha: -0.044, 95% CI: -0.485 to 0.413; CRP: 0.117, 95% CI: -0.216 to 0.458; metabolic syndrome 1.015;95% CI: -1.383 to 3.869) (Fig. 2).