We therefore sought to examine the relationship between the core cerebrospinal fluid (CSF) biomarkers of AD, amyloid-β1−42 (Aβ42), total-tau (T-tau), tau phosphorylated at threonine 181 (P-tau181), and alcohol consumption in a well-characterized population of older people derived from the Gothenburg H70 Birth Cohort Studies. Here, MAPT is linked to Alzheimer disease.