MKI67 and neoplasm: Tumor tissues from mice treated with AZD4573 showed lower Ki-67 expression, with 6.5% in the AZD4573-treated mouse and 12% in the control mouse (p < 0.05) (Fig. 6C). Collectively, we could verify not only the interaction between T-R conflicts and DDX25 helicases, but also the impact they have on cell proliferation in the xenograft model.