Both, direct PMP treatment of HMEC-1 and treatment of HMEC-1 with conditioned media from PMP-treated CRC cells resulted in a transcriptional suppression of PECAM1 (p = 0.002 for HMEC-1 + PBS vs. HMEC-1 + PMP; p = 0.001 for HMEC-1 + con. This evidence concerns the gene PECAM1 and colorectal carcinoma.