Moreover, the overexpression of FTO not only significantly promoted tumor growth (Fig. 2, L–O, shNC + Vector & shNC + FTO-FLAG, FDR < 0.05), but also reversed the growth inhibition induced by shSRSF6 (Fig. 2, L–O, shSRSF6 + Vector & shSRSF6 + FTO-FLAG, FDR < 0.01). This evidence concerns the gene FTO and neoplasm.