These specimens were used to examine the association between TILs and lymph node metastasis (LNM) in pT1b-SM cases.<h4>Results</h4>The number of CD4 + , CD8 + , and FoxP3 + TILs infiltrating the tumor increased significantly with increasing invasion depth. Here, CD4 is linked to metastatic malignant neoplasm in the lymph nodes.