Tumor infiltration was numerically increased across a range of T-cell types for six of seven patients: Tregs (3/7 biopsy pairs), Ki67+ Tregs (3/7, of which 2 also displayed total Treg increases), CD8+ memory T cells (3/7), Ki67+ CD8+ proliferating T cells (4/7), CD4+ effector T cells (2/7), and GITR+ CD4+ effector T cells (2/7; Supplementary Fig S9A–S9G). The gene discussed is CD4; the disease is neoplasm.