The mutational analysis of KRAS exon 2 identified a novel KRAS mutation in codon 232 (ENSFCAT00000019265.5:c.696A>T (p.Gln232His)) (Figure 1) in two epithelial tumors of the follicular pattern (2/16, 13%), one TNA and one TWA, both presenting multiple tumor foci within the same thyroid lobe. This evidence concerns the gene KRAS and neoplasm.