We analyzed the levels of TNF-α and IL-1β mRNA in IFN-γ/TNF-α-induced HaCaT cells by RT-qPCR (Figure S2), and the mRNA levels of TNF-α and IL-1β were elevated in the AD cell model constructed from IFN-γ/TNF-α-induced HaCaT cells. The gene discussed is IL1B; the disease is Alzheimer disease.