MYH14 and myocarditis: A preclinical study by Axelrod et al. evaluated the role of α-myosin in a mouse model of ICI-related myocarditis [38]: it showed a substantial role in promoting highly inflamed cardiac T-cells at the time of death due to myocarditis, suggesting α-myosin-reactive T-cell receptors (TCRs) not only as a mechanistic insight but also as a potential diagnostic biomarker and therapeutic target for selective immune modulation.