This analysis identified nine multigene and intragenic CNVs associated with DCM phenotype in different patients: a large multigene deletion of 13.7 Mb, the loss of GATA binding protein 4 (GATA4; OMIM *600576) sequence due to a 3.7 Mb deletion and a 51.9 Kb deletion within T-box transcription factor 20 (TBX20; OMIM *606061). Here, GATA4 is linked to familial dilated cardiomyopathy.