KDIGO has identified three osteodystrophy markers represented by the TMV system (turnover, mineralization, and volume) [6]: (a) osteitis fibrosa cystica: high bone turnover and hyperparathyroidism; (b) adynamic bone disease: low turnover due to PTH suppression; and (c) osteomalacia: low bone turnover and slow bone mineralization (less frequent due to the reduced prescription of aluminum-based phosphorus binders and improved dialysis concentrates) [13]. This evidence concerns the gene PTH and osteitis fibrosa.