Furthermore, comparing the highest and the lowest quintiles revealed an odds ratio of 1.39 (95% CI: 1.03–1.88; p for trend = 0.03) for hyperuricemia.These findings were replicated in a smaller Malaysian cohort study [67], which found that an increase in serum PTH levels was positively associated with an increase in UA levels (β = 0.165; p = 0.001). The gene discussed is PTH; the disease is hyperuricemia.