Lyso-Gb1 levels correlated with CHITO (r = 0.59 p < 0.001), CCL18 (r = 0.62 p < 0.001), hepatomegaly (r = 0.28 p < 0.001), splenomegaly (r = 0.27 p = 0.003), treatment mode (p < 0.001) and, interestingly, splenectomy (p = 0.01). The gene discussed is GABBR1; the disease is Splenomegaly.