Conversely, PC(16:0/18:1(9Z)), a metabolite significantly downregulated in ARMS, showed negative correlations with ARMS-unique proteins (cyclin-E1, r = −0.71; myotrophin, r = −0.68), which may reflect subtype-specific alterations in lipid metabolism related to tumor progression (Figure 4g). Here, CCNE1 is linked to neoplasm.