Tumor-associated angiogenic pathways, including blood vessel development and vascular remodeling were also enriched with major contribution of myosin-9 (MYH9), endoglin (ENG), thrombospondin-1 (THBS1), fibronectin (FN1), platelet factor 4 (PF4), phospholipase D (PLD1), filamin A (FLNA), and angiotensin-converting enzyme (ACE). This evidence concerns the gene PLD1 and neoplasm.