Also, the authors did not find any link between AD and von Willebrand factor, coagulation factor VIII, PAI-1, ADAM with thrombospondin type 1 motif, member 13 (ADAMTS13), plasmin, endogenous thrombin potential, and coagulation factor VII; however, they do suggest more research and data are required on those factors. This evidence concerns the gene VWF and Alzheimer disease.