MYC and posterior cortical atrophy: This study demonstrated that PCa with high GS levels was enriched for all five hallmark cell proliferation-related gene sets (E2F targets, the G2M checkpoint, the mitotic spindle, and MYC targets v1 and v2) and was significantly associated with high levels of the infiltrating fraction of several immune cells (CD4+ memory T cells, DCs, macrophage M1, and Th2 cells).