PDL1 TPS scores were found to be significantly positively correlated with lower blood CD4+T-cell count (p = 0.000), lower LDH (p = 0.020), higher CSF chloride (p = 0.000), location in the lateral ventricles and basal ganglia (p = 0.019), ABC-like DLBCL (p = 0.004), necrosis area (p = 0.000), higher expression of BCL2 (p = 0.005), lower expression of c-MYC (p = 0.003), positive expression of EBER (p = 0.000), and lower PD1 TPS (p = 0.039). This evidence concerns the gene CD4 and diffuse large B-cell lymphoma.