PDL1 gain and/or amplification was detected in squamous cell cancer of the lung (4.5% amplification) [30], non-small-cell lung cancer (3.1% amplification) [31], advanced melanomas (13.8% amplifications and 22.2% gains) [14], and squamous-cell carcinoma of the oral cavity [32] (19% amplification). The gene discussed is CD274; the disease is oral cavity squamous cell carcinoma.